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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA DUT CTRPv2 pan-cancer AAC 0.1 0.03
mRNA CDKN1C CTRPv2 pan-cancer AAC -0.08 0.03
mRNA ZNF473 CTRPv2 pan-cancer AAC 0.085 0.03
mRNA SNCA CTRPv2 pan-cancer AAC 0.094 0.03
mRNA SFSWAP CTRPv2 pan-cancer AAC 0.086 0.03
mRNA GPR84 CTRPv2 pan-cancer AAC 0.08 0.03
mRNA MRPL35 CTRPv2 pan-cancer AAC 0.083 0.03
mRNA STX19 CTRPv2 pan-cancer AAC -0.087 0.03
mRNA KHDRBS1 CTRPv2 pan-cancer AAC 0.087 0.03
mRNA MELTF CTRPv2 pan-cancer AAC -0.091 0.03
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