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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA PDCD11 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA CENPE CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA PPRC1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA NRDE2 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA RAD54L CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA ZNF680 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA RP11-65B7.2 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA NAGK CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA KCNMB3 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA RP11-15H20.8 CTRPv2 pan-cancer AAC 0.14 0.0002
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