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Compounds
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CD-437
CD-437
Synonyms
Sources
Names Used
CTRPv2
CD-437
PharmacoGx
CD-437
External IDs
Database
Identifier
Smiles:
CC1=CC(=CC(=C1OC)C)C=O
Inchikey:
SNIGEINPLSDHBQ-UHFFFAOYSA-N
Pubchem:
2758573
Annotated Targets
RARG
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with CD-437
(per dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
830
Download SVG
Number of tissues tested with CD-437 (per
dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
CD-437: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
0.55
0.60
NU-DUL-1
NU-DUL-1
SK-MM-2
SK-MM-2
SUP-M2
SUP-M2
OCI-AML2
OCI-AML2
EoL-1-cell
EoL-1-cell
COR-L279
COR-L279
HEL
HEL
TALL-1
TALL-1
697
697
MOLT-3
MOLT-3
SU-DHL-1
SU-DHL-1
P12-ICHIKAWA
P12-ICHIKAWA
CML-T1
CML-T1
L-540
L-540
NCI-H2228
NCI-H2228
JURL-MK1
JURL-MK1
CHP-126
CHP-126
D-283MED
D-283MED
SEM
SEM
MV-4-11
MV-4-11
M-07e
M-07e
MONO-MAC-1
MONO-MAC-1
YD-10B
YD-10B
NCI-H1105
NCI-H1105
KE-37
KE-37
MOLM-6
MOLM-6
NALM-6
NALM-6
DEL
DEL
NU-DHL-1
NU-DHL-1
JM1
JM1
Panc 05.04
Panc 05.04
NCI-H1563
NCI-H1563
HCC1419
HCC1419
ZR-75-1
ZR-75-1
NUGC-3
NUGC-3
HuH-28
HuH-28
CAL-120
CAL-120
NCI-H2172
NCI-H2172
HCC4006
HCC4006
NCI-H1792
NCI-H1792
HPAF-II
HPAF-II
PK-45H
PK-45H
KURAMOCHI
KURAMOCHI
BT320
BT320
CAKI-1
CAKI-1
Hep G2
Hep G2
BT422
BT422
KYSE-70
KYSE-70
KP-2
KP-2
KG-1-C
KG-1-C
Hs 822.T
Hs 822.T
PA-TU-8902
PA-TU-8902
COLO-205
COLO-205
TCC-PAN2
TCC-PAN2
SNU-213
SNU-213
MKN45
MKN45
NCI-H508
NCI-H508
SNU-387
SNU-387
JHH-6
JHH-6
RERF-LC-Ad1
RERF-LC-Ad1
NU-DUL-1
SK-MM-2
SUP-M2
OCI-AML2
EoL-1-cell
COR-L279
HEL
TALL-1
697
MOLT-3
SU-DHL-1
P12-ICHIKAWA
CML-T1
L-540
NCI-H2228
JURL-MK1
CHP-126
D-283MED
SEM
MV-4-11
M-07e
MONO-MAC-1
YD-10B
NCI-H1105
KE-37
MOLM-6
NALM-6
DEL
NU-DHL-1
JM1
Panc 05.04
NCI-H1563
HCC1419
ZR-75-1
NUGC-3
HuH-28
CAL-120
NCI-H2172
HCC4006
NCI-H1792
HPAF-II
PK-45H
KURAMOCHI
BT320
CAKI-1
Hep G2
BT422
KYSE-70
KP-2
KG-1-C
Hs 822.T
PA-TU-8902
COLO-205
TCC-PAN2
SNU-213
MKN45
NCI-H508
SNU-387
JHH-6
RERF-LC-Ad1
NU-DUL-1: 0.63
Synonyms: NU-DUL-1, NUDUL1
SK-MM-2: 0.61
Synonyms: SK-MM-2, SKMM2
SUP-M2: 0.56
Synonyms: SUP-M2, SUPM2
OCI-AML2: 0.55
Synonyms: OCI-AML2, OCIAML2
EoL-1-cell: 0.53
Synonyms: EoL-1-cell, EOL-1, EOL1
COR-L279: 0.52
Synonyms: COR-L279, CORL279
HEL: 0.51
Synonyms: HEL
TALL-1: 0.51
Synonyms: TALL-1, TALL1
697: 0.50
Synonyms: 697
MOLT-3: 0.50
Synonyms: MOLT-3, MOLT3
SU-DHL-1: 0.49
Synonyms: SU-DHL-1, SUDHL1
P12-ICHIKAWA: 0.49
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
CML-T1: 0.49
Synonyms: CML-T1, CMLT1
L-540: 0.48
Synonyms: L-540, L540
NCI-H2228: 0.48
Synonyms: NCI-H2228, NCIH2228
JURL-MK1: 0.48
Synonyms: JURL-MK1, JURLMK1
CHP-126: 0.48
Synonyms: CHP-126, CHP126
D-283MED: 0.48
Synonyms: D-283MED, D283 Med, D283_Med, D283MED
SEM: 0.48
Synonyms: SEM
MV-4-11: 0.48
Synonyms: MV-4-11, MV411
M-07e: 0.48
Synonyms: M-07e, M07E
MONO-MAC-1: 0.47
Synonyms: MONO-MAC-1, MONOMAC1
YD-10B: 0.47
Synonyms: YD-10B, YD10B
NCI-H1105: 0.47
Synonyms: NCI-H1105, NCIH1105
KE-37: 0.47
Synonyms: KE-37, KE37
MOLM-6: 0.46
Synonyms: MOLM-6, MOLM6
NALM-6: 0.46
Synonyms: NALM-6, NALM6
DEL: 0.46
Synonyms: DEL
NU-DHL-1: 0.45
Synonyms: NU-DHL-1, NUDHL1
JM1: 0.45
Synonyms: JM1
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
Panc 05.04: 0.04
Synonyms: Panc 05.04, Panc_05.04, PANC0504
NCI-H1563: 0.04
Synonyms: NCI-H1563, NCIH1563
HCC1419: 0.04
Synonyms: HCC1419, hcc1419
ZR-75-1: 0.04
Synonyms: ZR-75-1, ZR751, zr751
NUGC-3: 0.04
Synonyms: NUGC-3, NUGC3
HuH-28: 0.04
Synonyms: HuH-28, HuH28, HUH28
CAL-120: 0.04
Synonyms: CAL-120, CAL120, cal120
NCI-H2172: 0.04
Synonyms: NCI-H2172, NCIH2172
HCC4006: 0.03
Synonyms: HCC4006
NCI-H1792: 0.03
Synonyms: NCI-H1792, NCIH1792
HPAF-II: 0.03
Synonyms: HPAF-II, HPAFII
PK-45H: 0.03
Synonyms: PK-45H, PK45H
KURAMOCHI: 0.03
Synonyms: KURAMOCHI
BT320: 0.03
Synonyms: BT320
CAKI-1: 0.03
Synonyms: CAKI-1, Caki-1, CAKI1
Hep G2: 0.02
Synonyms: Hep G2, Hep_G2, HEPG2
BT422: 0.02
Synonyms: BT422
KYSE-70: 0.02
Synonyms: KYSE-70, KYSE70
KP-2: 0.02
Synonyms: KP-2, KP2
KG-1-C: 0.02
Synonyms: KG-1-C, KG1C
Hs 822.T: 0.01
Synonyms: Hs 822.T, Hs_822.T, HS822T
PA-TU-8902: 0.01
Synonyms: PA-TU-8902, PATU8902
COLO-205: 0.01
Synonyms: COLO-205, COLO 205, COLO205
TCC-PAN2: 0.01
Synonyms: TCC-PAN2, TCCPAN2
SNU-213: 0.01
Synonyms: SNU-213, SNU213
MKN45: 0.01
Synonyms: MKN45, MKN-45
NCI-H508: 0.01
Synonyms: NCI-H508, NCIH508
SNU-387: 0.00
Synonyms: SNU-387, SNU387
JHH-6: 0.00
Synonyms: JHH-6, JHH6
RERF-LC-Ad1: 0.00
Synonyms: RERF-LC-Ad1, RERFLCAD1
Download SVG
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
18.00
KNS81
KNS81
Panc 05.04
Panc 05.04
SUIT-2
SUIT-2
Hs 888.T
Hs 888.T
SNU-410
SNU-410
COLO-792
COLO-792
BT224
BT224
SK-MEL-31
SK-MEL-31
COLO-678
COLO-678
SNU-475
SNU-475
SNU-489
SNU-489
NCI-H1755
NCI-H1755
SK-MEL-3
SK-MEL-3
TUHR14TKB
TUHR14TKB
MDA-MB-361
MDA-MB-361
SNU-201
SNU-201
PK-45H
PK-45H
BT498
BT498
MOLP-2
MOLP-2
EFE-184
EFE-184
NCI-H2342
NCI-H2342
PANC-1
PANC-1
BT216
BT216
NCI-H889
NCI-H889
SK-LMS-1
SK-LMS-1
BT482
BT482
ACC-MESO-1
ACC-MESO-1
NCI-H2291
NCI-H2291
BT333
BT333
SNU-840
SNU-840
COLO-320-HSR
COLO-320-HSR
HEL 92.1.7
HEL 92.1.7
KASUMI-2
KASUMI-2
LU-99A
LU-99A
697
697
KYM-1
KYM-1
CHP-126
CHP-126
OCI-AML3
OCI-AML3
SEM
SEM
TALL-1
TALL-1
AML-193
AML-193
M-07e
M-07e
JURL-MK1
JURL-MK1
MOLT-3
MOLT-3
NU-DHL-1
NU-DHL-1
JVM-3
JVM-3
JVM-2
JVM-2
COR-L279
COR-L279
NALM-6
NALM-6
D-283MED
D-283MED
EoL-1-cell
EoL-1-cell
P12-ICHIKAWA
P12-ICHIKAWA
SU-DHL-1
SU-DHL-1
CML-T1
CML-T1
MV-4-11
MV-4-11
OCI-AML2
OCI-AML2
HEL
HEL
SUP-M2
SUP-M2
C32
C32
NU-DUL-1
NU-DUL-1
KNS81
Panc 05.04
SUIT-2
Hs 888.T
SNU-410
COLO-792
BT224
SK-MEL-31
COLO-678
SNU-475
SNU-489
NCI-H1755
SK-MEL-3
TUHR14TKB
MDA-MB-361
SNU-201
PK-45H
BT498
MOLP-2
EFE-184
NCI-H2342
PANC-1
BT216
NCI-H889
SK-LMS-1
BT482
ACC-MESO-1
NCI-H2291
BT333
SNU-840
COLO-320-HSR
HEL 92.1.7
KASUMI-2
LU-99A
697
KYM-1
CHP-126
OCI-AML3
SEM
TALL-1
AML-193
M-07e
JURL-MK1
MOLT-3
NU-DHL-1
JVM-3
JVM-2
COR-L279
NALM-6
D-283MED
EoL-1-cell
P12-ICHIKAWA
SU-DHL-1
CML-T1
MV-4-11
OCI-AML2
HEL
SUP-M2
C32
NU-DUL-1
KNS81: 18.83 (log10 µM)
Synonyms: KNS81
Panc 05.04: 12.71 (log10 µM)
Synonyms: Panc 05.04, Panc_05.04, PANC0504
SUIT-2: 11.97 (log10 µM)
Synonyms: SUIT-2, SUIT2
Hs 888.T: 8.81 (log10 µM)
Synonyms: Hs 888.T, Hs_888.T, HS888T
SNU-410: 4.02 (log10 µM)
Synonyms: SNU-410, SNU410
COLO-792: 3.82 (log10 µM)
Synonyms: COLO-792, COLO 792, COLO_792, COLO792
BT224: 3.32 (log10 µM)
Synonyms: BT224
SK-MEL-31: 2.93 (log10 µM)
Synonyms: SK-MEL-31, SKMEL31
COLO-678: 2.69 (log10 µM)
Synonyms: COLO-678, COLO 678, COLO678
SNU-475: 2.63 (log10 µM)
Synonyms: SNU-475, SNU475
SNU-489: 2.58 (log10 µM)
Synonyms: SNU-489, SNU489
NCI-H1755: 2.50 (log10 µM)
Synonyms: NCI-H1755, NCIH1755
SK-MEL-3: 2.47 (log10 µM)
Synonyms: SK-MEL-3, SKMEL3
TUHR14TKB: 2.36 (log10 µM)
Synonyms: TUHR14TKB
MDA-MB-361: 2.36 (log10 µM)
Synonyms: MDA-MB-361, MDAMB361, mdamb361
SNU-201: 2.36 (log10 µM)
Synonyms: SNU-201, SNU201
PK-45H: 2.22 (log10 µM)
Synonyms: PK-45H, PK45H
BT498: 2.20 (log10 µM)
Synonyms: BT498
MOLP-2: 2.19 (log10 µM)
Synonyms: MOLP-2, MOLP2
EFE-184: 1.93 (log10 µM)
Synonyms: EFE-184, EFE184
NCI-H2342: 1.90 (log10 µM)
Synonyms: NCI-H2342, NCIH2342
PANC-1: 1.88 (log10 µM)
Synonyms: PANC-1, PANC1
BT216: 1.82 (log10 µM)
Synonyms: BT216
NCI-H889: 1.81 (log10 µM)
Synonyms: NCI-H889, NCIH889
SK-LMS-1: 1.80 (log10 µM)
Synonyms: SK-LMS-1, SKLMS1
BT482: 1.73 (log10 µM)
Synonyms: BT482
ACC-MESO-1: 1.65 (log10 µM)
Synonyms: ACC-MESO-1, ACCMESO1
NCI-H2291: 1.63 (log10 µM)
Synonyms: NCI-H2291, NCIH2291
BT333: 1.63 (log10 µM)
Synonyms: BT333
SNU-840: 1.63 (log10 µM)
Synonyms: SNU-840, SNU840
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
COLO-320-HSR: -0.68 (log10 µM)
Synonyms: COLO-320-HSR, COLO-320, NA, COLO 320HSR, COLO320
HEL 92.1.7: -0.68 (log10 µM)
Synonyms: HEL 92.1.7, HEL_92.1.7, HEL9217
KASUMI-2: -0.69 (log10 µM)
Synonyms: KASUMI-2, KASUMI2
LU-99A: -0.69 (log10 µM)
Synonyms: LU-99A, LU99
697: -0.70 (log10 µM)
Synonyms: 697
KYM-1: -0.70 (log10 µM)
Synonyms: KYM-1, KYM1
CHP-126: -0.71 (log10 µM)
Synonyms: CHP-126, CHP126
OCI-AML3: -0.72 (log10 µM)
Synonyms: OCI-AML3, OCIAML3
SEM: -0.72 (log10 µM)
Synonyms: SEM
TALL-1: -0.73 (log10 µM)
Synonyms: TALL-1, TALL1
AML-193: -0.73 (log10 µM)
Synonyms: AML-193, AML193
M-07e: -0.74 (log10 µM)
Synonyms: M-07e, M07E
JURL-MK1: -0.75 (log10 µM)
Synonyms: JURL-MK1, JURLMK1
MOLT-3: -0.75 (log10 µM)
Synonyms: MOLT-3, MOLT3
NU-DHL-1: -0.78 (log10 µM)
Synonyms: NU-DHL-1, NUDHL1
JVM-3: -0.79 (log10 µM)
Synonyms: JVM-3, JVM3
JVM-2: -0.79 (log10 µM)
Synonyms: JVM-2, JVM2
COR-L279: -0.79 (log10 µM)
Synonyms: COR-L279, CORL279
NALM-6: -0.81 (log10 µM)
Synonyms: NALM-6, NALM6
D-283MED: -0.84 (log10 µM)
Synonyms: D-283MED, D283 Med, D283_Med, D283MED
EoL-1-cell: -0.86 (log10 µM)
Synonyms: EoL-1-cell, EOL-1, EOL1
P12-ICHIKAWA: -0.86 (log10 µM)
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
SU-DHL-1: -0.94 (log10 µM)
Synonyms: SU-DHL-1, SUDHL1
CML-T1: -0.95 (log10 µM)
Synonyms: CML-T1, CMLT1
MV-4-11: -0.95 (log10 µM)
Synonyms: MV-4-11, MV411
OCI-AML2: -0.97 (log10 µM)
Synonyms: OCI-AML2, OCIAML2
HEL: -0.97 (log10 µM)
Synonyms: HEL
SUP-M2: -1.00 (log10 µM)
Synonyms: SUP-M2, SUPM2
C32: -1.43 (log10 µM)
Synonyms: C32
NU-DUL-1: -1.70 (log10 µM)
Synonyms: NU-DUL-1, NUDUL1
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
CD-437: AAC
AAC
Tissues
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
0.55
0.60
cervix
cervix
pancreas
pancreas
pleura
pleura
kidney
kidney
skin
skin
prostate
prostate
liver
liver
biliary_tract
biliary_tract
breast
breast
stomach
stomach
central_nervous_system
central_nervous_system
ovary
ovary
unknown
unknown
endometrium
endometrium
thyroid
thyroid
upper_aerodigestive_tract
upper_aerodigestive_tract
lung
lung
soft_tissue
soft_tissue
large_intestine
large_intestine
oesophagus
oesophagus
urinary_tract
urinary_tract
bone
bone
salivary_gland
salivary_gland
autonomic_ganglia
autonomic_ganglia
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
-2.00
-1.50
-1.00
-0.50
0.00
0.50
1.00
1.50
2.00
2.50
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
salivary_gland
salivary_gland
autonomic_ganglia
autonomic_ganglia
bone
bone
oesophagus
oesophagus
upper_aerodigestive_tract
upper_aerodigestive_tract
stomach
stomach
ovary
ovary
lung
lung
cervix
cervix
endometrium
endometrium
large_intestine
large_intestine
breast
breast
soft_tissue
soft_tissue
thyroid
thyroid
urinary_tract
urinary_tract
skin
skin
pancreas
pancreas
central_nervous_system
central_nervous_system
liver
liver
kidney
kidney
prostate
prostate
pleura
pleura
biliary_tract
biliary_tract
unknown
unknown
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to CD-437
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
TPR
CTRPv2
pan-cancer
AAC
0.19
2e-09
mRNA
TIMELESS
CTRPv2
pan-cancer
AAC
0.2
2e-09
mRNA
LUC7L
CTRPv2
pan-cancer
AAC
0.21
2e-09
mRNA
ARHGAP19
CTRPv2
pan-cancer
AAC
0.24
2e-09
mRNA
ZNF195
CTRPv2
pan-cancer
AAC
0.21
2e-09
mRNA
ATXN7L2
CTRPv2
pan-cancer
AAC
0.2
2e-09
mRNA
KLHL8
CTRPv2
pan-cancer
AAC
0.21
2e-09
mRNA
H3F3A
CTRPv2
pan-cancer
AAC
0.21
3e-09
mRNA
AP003419.11
CTRPv2
pan-cancer
AAC
-0.19
3e-09
mRNA
RBM25
CTRPv2
pan-cancer
AAC
0.2
3e-09
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