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BIX-01294

BIX-01294

Synonyms

Sources	Names Used
CTRPv2	BIX-01294
PharmacoGx	BIX-01294

External IDs

Database	Identifier
Smiles:	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC
Inchikey:	OSXFATOLZGZLSK-UHFFFAOYSA-N
Pubchem:	25150857

Annotated Targets

EHMT1, EHMT2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX-01294

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF443	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	RRAS	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	SLIT1	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	PRPF39	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	SH2B1	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	SRP9	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	ADAMTSL5	CTRPv2	pan-cancer	AAC	-0.11	0.001
mRNA	DCAF6	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	CCDC14	CTRPv2	pan-cancer	AAC	0.11	0.001
mRNA	SLC25A52	CTRPv2	pan-cancer	AAC	0.11	0.001

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