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BIX-01294

BIX-01294

Synonyms

Sources	Names Used
CTRPv2	BIX-01294
PharmacoGx	BIX-01294

External IDs

Database	Identifier
Smiles:	CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC
Inchikey:	OSXFATOLZGZLSK-UHFFFAOYSA-N
Pubchem:	25150857

Annotated Targets

EHMT1, EHMT2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to BIX-01294

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	N4BP2	CTRPv2	pan-cancer	AAC	0.24	3e-10
mRNA	KMT2C	CTRPv2	pan-cancer	AAC	0.23	3e-10
mRNA	CPSF7	CTRPv2	pan-cancer	AAC	0.23	4e-10
mRNA	RAB39A	CTRPv2	pan-cancer	AAC	0.23	4e-10
mRNA	E2F2	CTRPv2	pan-cancer	AAC	0.25	4e-10
mRNA	AP3B2	CTRPv2	pan-cancer	AAC	0.23	4e-10
mRNA	CELF4	CTRPv2	pan-cancer	AAC	0.22	5e-10
mRNA	PPP1R3E	CTRPv2	pan-cancer	AAC	0.22	5e-10
mRNA	KLF12	CTRPv2	pan-cancer	AAC	0.22	6e-10
mRNA	SMIM17	CTRPv2	pan-cancer	AAC	0.21	7e-10

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