About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
SKI-II
SKI-II
Synonyms
Sources
Names Used
CTRPv2
SKI-II
PharmacoGx
SKI-II
External IDs
Database
Identifier
Smiles:
C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
Inchikey:
ZFGXZJKLOFCECI-UHFFFAOYSA-N
Pubchem:
753704
Annotated Targets
SPHK1
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with SKI-II (per
dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
805
Download SVG
Number of tissues tested with SKI-II (per
dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
SKI-II: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
BT416
BT416
CHP-126
CHP-126
EoL-1-cell
EoL-1-cell
DMS-79
DMS-79
BT172
BT172
NALM-6
NALM-6
BT422
BT422
SNU-182
SNU-182
GA-10
GA-10
Daudi
Daudi
PLC-PRF-5
PLC-PRF-5
OCI-M1
OCI-M1
NCI-H1341
NCI-H1341
PEER
PEER
MHH-CALL-4
MHH-CALL-4
ST486
ST486
MOLP-8
MOLP-8
BT164
BT164
TALL-1
TALL-1
RPMI-8402
RPMI-8402
SKM-1
SKM-1
OCI-LY3
OCI-LY3
A673
A673
Pfeiffer
Pfeiffer
AU565
AU565
KE-37
KE-37
SUP-T11
SUP-T11
P31-FUJ
P31-FUJ
SU.86.86
SU.86.86
NCI-H2141
NCI-H2141
JMSU-1
JMSU-1
SW1710
SW1710
JIMT-1
JIMT-1
BCPAP
BCPAP
CGTH-W-1
CGTH-W-1
COLO-680N
COLO-680N
ECC12
ECC12
SNU-1196
SNU-1196
SNU-8
SNU-8
HARA
HARA
LU-99A
LU-99A
DLD-1
DLD-1
SNU-620
SNU-620
MKN45
MKN45
SBC-5
SBC-5
KMS-27
KMS-27
NCI-H1838
NCI-H1838
SNU-668
SNU-668
SNU-899
SNU-899
TE-9
TE-9
YD-38
YD-38
NCI-H2444
NCI-H2444
MCAS
MCAS
SK-MEL-28
SK-MEL-28
MDA-MB-435
MDA-MB-435
OE33
OE33
SH-4
SH-4
SK-MEL-2
SK-MEL-2
HCC1419
HCC1419
SK-MEL-3
SK-MEL-3
BT416
CHP-126
EoL-1-cell
DMS-79
BT172
NALM-6
BT422
SNU-182
GA-10
Daudi
PLC-PRF-5
OCI-M1
NCI-H1341
PEER
MHH-CALL-4
ST486
MOLP-8
BT164
TALL-1
RPMI-8402
SKM-1
OCI-LY3
A673
Pfeiffer
AU565
KE-37
SUP-T11
P31-FUJ
SU.86.86
NCI-H2141
JMSU-1
SW1710
JIMT-1
BCPAP
CGTH-W-1
COLO-680N
ECC12
SNU-1196
SNU-8
HARA
LU-99A
DLD-1
SNU-620
MKN45
SBC-5
KMS-27
NCI-H1838
SNU-668
SNU-899
TE-9
YD-38
NCI-H2444
MCAS
SK-MEL-28
MDA-MB-435
OE33
SH-4
SK-MEL-2
HCC1419
SK-MEL-3
BT416: 0.32
Synonyms: BT416
CHP-126: 0.26
Synonyms: CHP-126, CHP126
EoL-1-cell: 0.24
Synonyms: EoL-1-cell, EOL-1, EOL1
DMS-79: 0.24
Synonyms: DMS-79, DMS 79, DMS_79, DMS79
BT172: 0.24
Synonyms: BT172
NALM-6: 0.22
Synonyms: NALM-6, NALM6
BT422: 0.22
Synonyms: BT422
SNU-182: 0.21
Synonyms: SNU-182, SNU182
GA-10: 0.21
Synonyms: GA-10, GA10
Daudi: 0.21
Synonyms: Daudi, DAUDI
PLC-PRF-5: 0.20
Synonyms: PLC-PRF-5, PLC/PRF/5, PLC_PRF_5, PLCPRF5
OCI-M1: 0.20
Synonyms: OCI-M1, OCIM1
NCI-H1341: 0.19
Synonyms: NCI-H1341, NCIH1341
PEER: 0.19
Synonyms: PEER
MHH-CALL-4: 0.19
Synonyms: MHH-CALL-4, MHHCALL4
ST486: 0.18
Synonyms: ST486
MOLP-8: 0.18
Synonyms: MOLP-8, MOLP8
BT164: 0.17
Synonyms: BT164
TALL-1: 0.17
Synonyms: TALL-1, TALL1
RPMI-8402: 0.17
Synonyms: RPMI-8402, RPMI8402
SKM-1: 0.17
Synonyms: SKM-1, SKM1
OCI-LY3: 0.17
Synonyms: OCI-LY3, OCI-LY-3, OCILY3
A673: 0.17
Synonyms: A673, A-673
Pfeiffer: 0.16
Synonyms: Pfeiffer, PFEIFFER
AU565: 0.16
Synonyms: AU565, au565
KE-37: 0.16
Synonyms: KE-37, KE37
SUP-T11: 0.16
Synonyms: SUP-T11, SUPT11
P31-FUJ: 0.16
Synonyms: P31-FUJ, P31/FUJ, P31_FUJ, P31FUJ
SU.86.86: 0.16
Synonyms: SU.86.86, SU8686
NCI-H2141: 0.16
Synonyms: NCI-H2141, NCIH2141
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
JMSU-1: 0.00
Synonyms: JMSU-1, JMSU1
SW1710: 0.00
Synonyms: SW1710, SW-1710
JIMT-1: 0.00
Synonyms: JIMT-1, JIMT1, jimt1
BCPAP: 0.00
Synonyms: BCPAP, B-CPAP
CGTH-W-1: 0.00
Synonyms: CGTH-W-1, CGTHW1
COLO-680N: 0.00
Synonyms: COLO-680N, COLO 680N, COLO680N
ECC12: 0.00
Synonyms: ECC12
SNU-1196: 0.00
Synonyms: SNU-1196, SNU1196
SNU-8: 0.00
Synonyms: SNU-8, SNU8
HARA: 0.00
Synonyms: HARA
LU-99A: 0.00
Synonyms: LU-99A, LU99
DLD-1: 0.00
Synonyms: DLD-1, DLD1
SNU-620: 0.00
Synonyms: SNU-620, SNU620
MKN45: 0.00
Synonyms: MKN45, MKN-45
SBC-5: 0.00
Synonyms: SBC-5, SBC5
KMS-27: 0.00
Synonyms: KMS-27, KMS27
NCI-H1838: 0.00
Synonyms: NCI-H1838, NCIH1838
SNU-668: 0.00
Synonyms: SNU-668, SNU668
SNU-899: 0.00
Synonyms: SNU-899, SNU899
TE-9: 0.00
Synonyms: TE-9, TE9
YD-38: 0.00
Synonyms: YD-38, YD38
NCI-H2444: 0.00
Synonyms: NCI-H2444, NCIH2444
MCAS: 0.00
Synonyms: MCAS
SK-MEL-28: 0.00
Synonyms: SK-MEL-28, SKMEL28
MDA-MB-435: 0.00
Synonyms: MDA-MB-435, MDA-MB-435S, MDAMB435S
OE33: 0.00
Synonyms: OE33
SH-4: 0.00
Synonyms: SH-4, SH4
SK-MEL-2: 0.00
Synonyms: SK-MEL-2, SKMEL2
HCC1419: 0.00
Synonyms: HCC1419, hcc1419
SK-MEL-3: 0.00
Synonyms: SK-MEL-3, SKMEL3
Download SVG
0.00
2.00
4.00
6.00
8.00
10.00
12.00
14.00
16.00
JHOC-5
JHOC-5
LOU-NH91
LOU-NH91
COLO-829
COLO-829
5637
5637
NCI-N87
NCI-N87
DU-4475
DU-4475
NCI-H1563
NCI-H1563
JL-1
JL-1
T3M-10
T3M-10
SNU-449
SNU-449
SW 1353
SW 1353
C2BBe1
C2BBe1
Panc 02.03
Panc 02.03
HDLM-2
HDLM-2
SNU-1105
SNU-1105
BT320
BT320
TE-14
TE-14
BxPC-3
BxPC-3
Panc 04.03
Panc 04.03
GAMG
GAMG
KP-2
KP-2
LC-1/sq-SF
LC-1/sq-SF
ZR-75-30
ZR-75-30
KYSE-70
KYSE-70
SW48
SW48
RL95-2
RL95-2
NCI-H2342
NCI-H2342
OVCAR-4
OVCAR-4
NCI-H2085
NCI-H2085
253J-BV
253J-BV
Pfeiffer
Pfeiffer
KASUMI-1
KASUMI-1
BT112
BT112
SK-MM-2
SK-MM-2
MEC-1
MEC-1
JURKAT
JURKAT
OCI-LY3
OCI-LY3
JM1
JM1
P12-ICHIKAWA
P12-ICHIKAWA
NCI-H2141
NCI-H2141
MOLT-13
MOLT-13
P31-FUJ
P31-FUJ
IMR-32
IMR-32
KE-37
KE-37
RPMI-8402
RPMI-8402
A673
A673
BT164
BT164
MOLP-8
MOLP-8
D-283MED
D-283MED
ST486
ST486
PEER
PEER
SUP-T11
SUP-T11
Daudi
Daudi
OCI-M1
OCI-M1
SKM-1
SKM-1
NCI-H1341
NCI-H1341
MHH-CALL-4
MHH-CALL-4
GA-10
GA-10
NALM-6
NALM-6
TALL-1
TALL-1
JHOC-5
LOU-NH91
COLO-829
5637
NCI-N87
DU-4475
NCI-H1563
JL-1
T3M-10
SNU-449
SW 1353
C2BBe1
Panc 02.03
HDLM-2
SNU-1105
BT320
TE-14
BxPC-3
Panc 04.03
GAMG
KP-2
LC-1/sq-SF
ZR-75-30
KYSE-70
SW48
RL95-2
NCI-H2342
OVCAR-4
NCI-H2085
253J-BV
Pfeiffer
KASUMI-1
BT112
SK-MM-2
MEC-1
JURKAT
OCI-LY3
JM1
P12-ICHIKAWA
NCI-H2141
MOLT-13
P31-FUJ
IMR-32
KE-37
RPMI-8402
A673
BT164
MOLP-8
D-283MED
ST486
PEER
SUP-T11
Daudi
OCI-M1
SKM-1
NCI-H1341
MHH-CALL-4
GA-10
NALM-6
TALL-1
JHOC-5: 16.89 (log10 µM)
Synonyms: JHOC-5, JHOC5
LOU-NH91: 16.75 (log10 µM)
Synonyms: LOU-NH91, LOUNH91
COLO-829: 15.34 (log10 µM)
Synonyms: COLO-829, COLO 829, COLO_829, COLO829
5637: 15.00 (log10 µM)
Synonyms: 5637
NCI-N87: 14.71 (log10 µM)
Synonyms: NCI-N87, NCIN87
DU-4475: 14.16 (log10 µM)
Synonyms: DU-4475, DU4475, du4475
NCI-H1563: 12.05 (log10 µM)
Synonyms: NCI-H1563, NCIH1563
JL-1: 11.38 (log10 µM)
Synonyms: JL-1, JL1
T3M-10: 11.25 (log10 µM)
Synonyms: T3M-10, T3M10
SNU-449: 9.96 (log10 µM)
Synonyms: SNU-449, SNU449
SW 1353: 9.56 (log10 µM)
Synonyms: SW 1353, SW_1353, SW1353
C2BBe1: 8.84 (log10 µM)
Synonyms: C2BBe1, C2BBE1
Panc 02.03: 8.72 (log10 µM)
Synonyms: Panc 02.03, Panc_02.03, PANC-02-03, PANC0203
HDLM-2: 8.72 (log10 µM)
Synonyms: HDLM-2, HDLM2
SNU-1105: 7.80 (log10 µM)
Synonyms: SNU-1105, SNU1105
BT320: 7.80 (log10 µM)
Synonyms: BT320
TE-14: 7.79 (log10 µM)
Synonyms: TE-14, TE14
BxPC-3: 7.39 (log10 µM)
Synonyms: BxPC-3, BXPC3
Panc 04.03: 7.21 (log10 µM)
Synonyms: Panc 04.03, Panc_04.03, PANC-04-03, PANC0403
GAMG: 6.67 (log10 µM)
Synonyms: GAMG
KP-2: 6.60 (log10 µM)
Synonyms: KP-2, KP2
LC-1/sq-SF: 6.19 (log10 µM)
Synonyms: LC-1/sq-SF, LC1SQSF
ZR-75-30: 6.09 (log10 µM)
Synonyms: ZR-75-30, ZR7530, zr7530
KYSE-70: 6.00 (log10 µM)
Synonyms: KYSE-70, KYSE70
SW48: 6.00 (log10 µM)
Synonyms: SW48, SW 48
RL95-2: 5.74 (log10 µM)
Synonyms: RL95-2, RL952
NCI-H2342: 5.70 (log10 µM)
Synonyms: NCI-H2342, NCIH2342
OVCAR-4: 5.58 (log10 µM)
Synonyms: OVCAR-4, OVCAR4
NCI-H2085: 5.53 (log10 µM)
Synonyms: NCI-H2085, NCIH2085
253J-BV: 5.51 (log10 µM)
Synonyms: 253J-BV, 253JBV
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
Pfeiffer: 1.50 (log10 µM)
Synonyms: Pfeiffer, PFEIFFER
KASUMI-1: 1.49 (log10 µM)
Synonyms: KASUMI-1, Kasumi-1, KASUMI1
BT112: 1.48 (log10 µM)
Synonyms: BT112
SK-MM-2: 1.48 (log10 µM)
Synonyms: SK-MM-2, SKMM2
MEC-1: 1.47 (log10 µM)
Synonyms: MEC-1, MEC1
JURKAT: 1.47 (log10 µM)
Synonyms: JURKAT, Jurkat
OCI-LY3: 1.46 (log10 µM)
Synonyms: OCI-LY3, OCI-LY-3, OCILY3
JM1: 1.45 (log10 µM)
Synonyms: JM1
P12-ICHIKAWA: 1.45 (log10 µM)
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
NCI-H2141: 1.44 (log10 µM)
Synonyms: NCI-H2141, NCIH2141
MOLT-13: 1.44 (log10 µM)
Synonyms: MOLT-13, MOLT13
P31-FUJ: 1.41 (log10 µM)
Synonyms: P31-FUJ, P31/FUJ, P31_FUJ, P31FUJ
IMR-32: 1.40 (log10 µM)
Synonyms: IMR-32, IMR32
KE-37: 1.39 (log10 µM)
Synonyms: KE-37, KE37
RPMI-8402: 1.36 (log10 µM)
Synonyms: RPMI-8402, RPMI8402
A673: 1.35 (log10 µM)
Synonyms: A673, A-673
BT164: 1.34 (log10 µM)
Synonyms: BT164
MOLP-8: 1.32 (log10 µM)
Synonyms: MOLP-8, MOLP8
D-283MED: 1.28 (log10 µM)
Synonyms: D-283MED, D283 Med, D283_Med, D283MED
ST486: 1.28 (log10 µM)
Synonyms: ST486
PEER: 1.28 (log10 µM)
Synonyms: PEER
SUP-T11: 1.21 (log10 µM)
Synonyms: SUP-T11, SUPT11
Daudi: 1.20 (log10 µM)
Synonyms: Daudi, DAUDI
OCI-M1: 1.19 (log10 µM)
Synonyms: OCI-M1, OCIM1
SKM-1: 1.19 (log10 µM)
Synonyms: SKM-1, SKM1
NCI-H1341: 1.17 (log10 µM)
Synonyms: NCI-H1341, NCIH1341
MHH-CALL-4: 1.14 (log10 µM)
Synonyms: MHH-CALL-4, MHHCALL4
GA-10: 1.13 (log10 µM)
Synonyms: GA-10, GA10
NALM-6: 1.12 (log10 µM)
Synonyms: NALM-6, NALM6
TALL-1: 1.10 (log10 µM)
Synonyms: TALL-1, TALL1
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
SKI-II: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
urinary_tract
urinary_tract
stomach
stomach
large_intestine
large_intestine
skin
skin
breast
breast
ovary
ovary
pancreas
pancreas
central_nervous_system
central_nervous_system
lung
lung
upper_aerodigestive_tract
upper_aerodigestive_tract
oesophagus
oesophagus
endometrium
endometrium
unknown
unknown
soft_tissue
soft_tissue
prostate
prostate
cervix
cervix
liver
liver
kidney
kidney
bone
bone
biliary_tract
biliary_tract
thyroid
thyroid
autonomic_ganglia
autonomic_ganglia
pleura
pleura
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
salivary_gland
salivary_gland
0.00
1.00
2.00
3.00
4.00
5.00
6.00
7.00
8.00
salivary_gland
salivary_gland
cervix
cervix
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
autonomic_ganglia
autonomic_ganglia
thyroid
thyroid
bone
bone
unknown
unknown
soft_tissue
soft_tissue
breast
breast
large_intestine
large_intestine
stomach
stomach
endometrium
endometrium
lung
lung
urinary_tract
urinary_tract
central_nervous_system
central_nervous_system
biliary_tract
biliary_tract
upper_aerodigestive_tract
upper_aerodigestive_tract
pancreas
pancreas
ovary
ovary
liver
liver
kidney
kidney
skin
skin
prostate
prostate
oesophagus
oesophagus
pleura
pleura
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to SKI-II
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
SRSF12
CTRPv2
pan-cancer
AAC
0.18
2e-05
mRNA
ZNF138
CTRPv2
pan-cancer
AAC
0.17
2e-05
mRNA
HOXD3
CTRPv2
pan-cancer
AAC
0.17
2e-05
mRNA
TRO
CTRPv2
pan-cancer
AAC
0.18
2e-05
mRNA
CCNT2
CTRPv2
pan-cancer
AAC
0.16
2e-05
mRNA
LRRC37B
CTRPv2
pan-cancer
AAC
0.16
2e-05
mRNA
CBX1
CTRPv2
pan-cancer
AAC
0.17
2e-05
mRNA
CTB-133G6.1
CTRPv2
pan-cancer
AAC
0.19
2e-05
mRNA
C7orf55-LUC7L2
CTRPv2
pan-cancer
AAC
0.17
2e-05
mRNA
HADH
CTRPv2
pan-cancer
AAC
0.18
2e-05
← Previous
1
2
…
18
19
20
…
199
200
Next →
Download CSV