About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
phloretin
phloretin
Synonyms
Sources
Names Used
CTRPv2
phloretin
PharmacoGx
phloretin
External IDs
Database
Identifier
Smiles:
CC(=O)C1=C(C=C(C=C1O)OC)O
Inchikey:
GKSGTWUNURZTKD-UHFFFAOYSA-N
Pubchem:
24135
Annotated Targets
AQP9
,
CLCN3
,
SLC23A1
,
SLC5A1
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with phloretin
(per dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
821
Download SVG
Number of tissues tested with phloretin
(per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
phloretin: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
EoL-1-cell
EoL-1-cell
LP-1
LP-1
MV-4-11
MV-4-11
Hs-578-T
Hs-578-T
COR-L51
COR-L51
NCI-H2141
NCI-H2141
BT239
BT239
KASUMI-1
KASUMI-1
CA46
CA46
P12-ICHIKAWA
P12-ICHIKAWA
PEER
PEER
KMS-28BM
KMS-28BM
TTC709
TTC709
JK-1
JK-1
IM-95
IM-95
KMS-26
KMS-26
JVM-2
JVM-2
697
697
KMS-34
KMS-34
EM-2
EM-2
Pfeiffer
Pfeiffer
BT428
BT428
KU812
KU812
BT416
BT416
COLO-320-HSR
COLO-320-HSR
HeLa
HeLa
HGC-27
HGC-27
KMS-20
KMS-20
NCI-H1975
NCI-H1975
NCI-H1341
NCI-H1341
NCI-H508
NCI-H508
BFTC-909
BFTC-909
GOS-3
GOS-3
EFO-27
EFO-27
RCM-1
RCM-1
BICR 31
BICR 31
CAL-78
CAL-78
KATOIII
KATOIII
SW982
SW982
EFO-21
EFO-21
CAL-29
CAL-29
SK-OV-3
SK-OV-3
RCC10RGB
RCC10RGB
KARPAS-620
KARPAS-620
PA-TU-8988T
PA-TU-8988T
KP-2
KP-2
DLD-1
DLD-1
CL-11
CL-11
RERF-LC-Ad1
RERF-LC-Ad1
BFTC-905
BFTC-905
BHT-101
BHT-101
COV362
COV362
SNU-489
SNU-489
HT-29
HT-29
NMC-G1
NMC-G1
YKG-1
YKG-1
ML-1
ML-1
CAL-120
CAL-120
TUHR4TKB
TUHR4TKB
CAL-62
CAL-62
EoL-1-cell
LP-1
MV-4-11
Hs-578-T
COR-L51
NCI-H2141
BT239
KASUMI-1
CA46
P12-ICHIKAWA
PEER
KMS-28BM
TTC709
JK-1
IM-95
KMS-26
JVM-2
697
KMS-34
EM-2
Pfeiffer
BT428
KU812
BT416
COLO-320-HSR
HeLa
HGC-27
KMS-20
NCI-H1975
NCI-H1341
NCI-H508
BFTC-909
GOS-3
EFO-27
RCM-1
BICR 31
CAL-78
KATOIII
SW982
EFO-21
CAL-29
SK-OV-3
RCC10RGB
KARPAS-620
PA-TU-8988T
KP-2
DLD-1
CL-11
RERF-LC-Ad1
BFTC-905
BHT-101
COV362
SNU-489
HT-29
NMC-G1
YKG-1
ML-1
CAL-120
TUHR4TKB
CAL-62
EoL-1-cell: 0.38
Synonyms: EoL-1-cell, EOL-1, EOL1
LP-1: 0.35
Synonyms: LP-1, LP1
MV-4-11: 0.35
Synonyms: MV-4-11, MV411
Hs-578-T: 0.33
Synonyms: Hs-578-T, Hs 578T, Hs_578T, HS578T, hs578t
COR-L51: 0.30
Synonyms: COR-L51, CORL51
NCI-H2141: 0.27
Synonyms: NCI-H2141, NCIH2141
BT239: 0.27
Synonyms: BT239
KASUMI-1: 0.26
Synonyms: KASUMI-1, Kasumi-1, KASUMI1
CA46: 0.26
Synonyms: CA46
P12-ICHIKAWA: 0.26
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
PEER: 0.26
Synonyms: PEER
KMS-28BM: 0.25
Synonyms: KMS-28BM, KMS28BM
TTC709: 0.25
Synonyms: TTC709
JK-1: 0.25
Synonyms: JK-1, JK1
IM-95: 0.25
Synonyms: IM-95, IM95
KMS-26: 0.25
Synonyms: KMS-26, KMS26
JVM-2: 0.24
Synonyms: JVM-2, JVM2
697: 0.24
Synonyms: 697
KMS-34: 0.24
Synonyms: KMS-34, KMS34
EM-2: 0.24
Synonyms: EM-2, EM2
Pfeiffer: 0.23
Synonyms: Pfeiffer, PFEIFFER
BT428: 0.23
Synonyms: BT428
KU812: 0.23
Synonyms: KU812
BT416: 0.23
Synonyms: BT416
COLO-320-HSR: 0.23
Synonyms: COLO-320-HSR, COLO-320, NA, COLO 320HSR, COLO320
HeLa: 0.23
Synonyms: HeLa, HELA
HGC-27: 0.23
Synonyms: HGC-27, HGC27
KMS-20: 0.23
Synonyms: KMS-20, KMS20
NCI-H1975: 0.23
Synonyms: NCI-H1975, NCIH1975
NCI-H1341: 0.22
Synonyms: NCI-H1341, NCIH1341
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
NCI-H508: 0.03
Synonyms: NCI-H508, NCIH508
BFTC-909: 0.03
Synonyms: BFTC-909, BFTC909
GOS-3: 0.03
Synonyms: GOS-3, GOS3
EFO-27: 0.03
Synonyms: EFO-27, EFO27
RCM-1: 0.03
Synonyms: RCM-1, RCM1
BICR 31: 0.03
Synonyms: BICR 31, BICR_31, BICR31
CAL-78: 0.03
Synonyms: CAL-78, CAL78
KATOIII: 0.03
Synonyms: KATOIII, KATO III, KATO_III
SW982: 0.03
Synonyms: SW982, SW 982
EFO-21: 0.03
Synonyms: EFO-21, EFO21
CAL-29: 0.03
Synonyms: CAL-29, CAL29
SK-OV-3: 0.03
Synonyms: SK-OV-3, SKOV3
RCC10RGB: 0.03
Synonyms: RCC10RGB
KARPAS-620: 0.03
Synonyms: KARPAS-620, KARPAS620
PA-TU-8988T: 0.03
Synonyms: PA-TU-8988T, PATU8988T
KP-2: 0.03
Synonyms: KP-2, KP2
DLD-1: 0.03
Synonyms: DLD-1, DLD1
CL-11: 0.03
Synonyms: CL-11, CL11
RERF-LC-Ad1: 0.03
Synonyms: RERF-LC-Ad1, RERFLCAD1
BFTC-905: 0.03
Synonyms: BFTC-905, BFTC905
BHT-101: 0.02
Synonyms: BHT-101, BHT101
COV362: 0.02
Synonyms: COV362
SNU-489: 0.02
Synonyms: SNU-489, SNU489
HT-29: 0.02
Synonyms: HT-29, HT29
NMC-G1: 0.02
Synonyms: NMC-G1, NMCG1
YKG-1: 0.02
Synonyms: YKG-1, YKG1
ML-1: 0.02
Synonyms: ML-1, ML1
CAL-120: 0.02
Synonyms: CAL-120, CAL120, cal120
TUHR4TKB: 0.01
Synonyms: TUHR4TKB
CAL-62: 0.01
Synonyms: CAL-62, CAL62
Download SVG
0.00
0.50
1.00
1.50
2.00
2.50
3.00
3.50
4.00
4.50
5.00
5.50
6.00
Hep G2
Hep G2
IM-95
IM-95
NMC-G1
NMC-G1
C2BBe1
C2BBe1
PA-TU-8902
PA-TU-8902
CAL-62
CAL-62
TUHR4TKB
TUHR4TKB
CL-11
CL-11
LCLC-97TM1
LCLC-97TM1
CAL-120
CAL-120
ML-1
ML-1
SW1710
SW1710
YKG-1
YKG-1
HT-29
HT-29
BHT-101
BHT-101
SNU-489
SNU-489
HCC-15
HCC-15
COV362
COV362
KP-2
KP-2
P3HR-1
P3HR-1
BFTC-905
BFTC-905
KARPAS-620
KARPAS-620
RERF-LC-Ad1
RERF-LC-Ad1
EFO-27
EFO-27
KATOIII
KATOIII
DLD-1
DLD-1
SNU-1196
SNU-1196
SNG-M
SNG-M
PA-TU-8988T
PA-TU-8988T
GAMG
GAMG
TYK-nu
TYK-nu
Pfeiffer
Pfeiffer
KELLY
KELLY
HeLa
HeLa
NCI-H1975
NCI-H1975
RL
RL
KMS-26
KMS-26
RPMI-8226
RPMI-8226
NALM-6
NALM-6
M-07e
M-07e
TALL-1
TALL-1
COLO-320-HSR
COLO-320-HSR
NCI-H1341
NCI-H1341
EM-2
EM-2
A204
A204
HGC-27
HGC-27
KMS-21BM
KMS-21BM
KMS-20
KMS-20
MOLT-13
MOLT-13
KMS-34
KMS-34
JVM-2
JVM-2
SK-N-MC
SK-N-MC
BT239
BT239
PEER
PEER
KMS-28BM
KMS-28BM
697
697
P12-ICHIKAWA
P12-ICHIKAWA
LP-1
LP-1
MV-4-11
MV-4-11
COR-L51
COR-L51
Hep G2
IM-95
NMC-G1
C2BBe1
PA-TU-8902
CAL-62
TUHR4TKB
CL-11
LCLC-97TM1
CAL-120
ML-1
SW1710
YKG-1
HT-29
BHT-101
SNU-489
HCC-15
COV362
KP-2
P3HR-1
BFTC-905
KARPAS-620
RERF-LC-Ad1
EFO-27
KATOIII
DLD-1
SNU-1196
SNG-M
PA-TU-8988T
GAMG
TYK-nu
Pfeiffer
KELLY
HeLa
NCI-H1975
RL
KMS-26
RPMI-8226
NALM-6
M-07e
TALL-1
COLO-320-HSR
NCI-H1341
EM-2
A204
HGC-27
KMS-21BM
KMS-20
MOLT-13
KMS-34
JVM-2
SK-N-MC
BT239
PEER
KMS-28BM
697
P12-ICHIKAWA
LP-1
MV-4-11
COR-L51
Hep G2: 6.00 (log10 µM)
Synonyms: Hep G2, Hep_G2, HEPG2
IM-95: 4.14 (log10 µM)
Synonyms: IM-95, IM95
NMC-G1: 3.55 (log10 µM)
Synonyms: NMC-G1, NMCG1
C2BBe1: 2.91 (log10 µM)
Synonyms: C2BBe1, C2BBE1
PA-TU-8902: 2.85 (log10 µM)
Synonyms: PA-TU-8902, PATU8902
CAL-62: 2.84 (log10 µM)
Synonyms: CAL-62, CAL62
TUHR4TKB: 2.81 (log10 µM)
Synonyms: TUHR4TKB
CL-11: 2.80 (log10 µM)
Synonyms: CL-11, CL11
LCLC-97TM1: 2.80 (log10 µM)
Synonyms: LCLC-97TM1, LCLC97TM1
CAL-120: 2.78 (log10 µM)
Synonyms: CAL-120, CAL120, cal120
ML-1: 2.77 (log10 µM)
Synonyms: ML-1, ML1
SW1710: 2.77 (log10 µM)
Synonyms: SW1710, SW-1710
YKG-1: 2.75 (log10 µM)
Synonyms: YKG-1, YKG1
HT-29: 2.73 (log10 µM)
Synonyms: HT-29, HT29
BHT-101: 2.73 (log10 µM)
Synonyms: BHT-101, BHT101
SNU-489: 2.73 (log10 µM)
Synonyms: SNU-489, SNU489
HCC-15: 2.71 (log10 µM)
Synonyms: HCC-15, HCC15
COV362: 2.71 (log10 µM)
Synonyms: COV362
KP-2: 2.70 (log10 µM)
Synonyms: KP-2, KP2
P3HR-1: 2.70 (log10 µM)
Synonyms: P3HR-1, P3HR1
BFTC-905: 2.70 (log10 µM)
Synonyms: BFTC-905, BFTC905
KARPAS-620: 2.69 (log10 µM)
Synonyms: KARPAS-620, KARPAS620
RERF-LC-Ad1: 2.69 (log10 µM)
Synonyms: RERF-LC-Ad1, RERFLCAD1
EFO-27: 2.69 (log10 µM)
Synonyms: EFO-27, EFO27
KATOIII: 2.69 (log10 µM)
Synonyms: KATOIII, KATO III, KATO_III
DLD-1: 2.67 (log10 µM)
Synonyms: DLD-1, DLD1
SNU-1196: 2.67 (log10 µM)
Synonyms: SNU-1196, SNU1196
SNG-M: 2.67 (log10 µM)
Synonyms: SNG-M, SNGM
PA-TU-8988T: 2.67 (log10 µM)
Synonyms: PA-TU-8988T, PATU8988T
GAMG: 2.67 (log10 µM)
Synonyms: GAMG
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
TYK-nu: 1.75 (log10 µM)
Synonyms: TYK-nu, TYKNU
Pfeiffer: 1.75 (log10 µM)
Synonyms: Pfeiffer, PFEIFFER
KELLY: 1.74 (log10 µM)
Synonyms: KELLY
HeLa: 1.73 (log10 µM)
Synonyms: HeLa, HELA
NCI-H1975: 1.73 (log10 µM)
Synonyms: NCI-H1975, NCIH1975
RL: 1.73 (log10 µM)
Synonyms: RL
KMS-26: 1.72 (log10 µM)
Synonyms: KMS-26, KMS26
RPMI-8226: 1.72 (log10 µM)
Synonyms: RPMI-8226, RPMI 8226, RPMI_8226, RPMI8226
NALM-6: 1.72 (log10 µM)
Synonyms: NALM-6, NALM6
M-07e: 1.71 (log10 µM)
Synonyms: M-07e, M07E
TALL-1: 1.71 (log10 µM)
Synonyms: TALL-1, TALL1
COLO-320-HSR: 1.70 (log10 µM)
Synonyms: COLO-320-HSR, COLO-320, NA, COLO 320HSR, COLO320
NCI-H1341: 1.70 (log10 µM)
Synonyms: NCI-H1341, NCIH1341
EM-2: 1.69 (log10 µM)
Synonyms: EM-2, EM2
A204: 1.69 (log10 µM)
Synonyms: A204, A-204
HGC-27: 1.68 (log10 µM)
Synonyms: HGC-27, HGC27
KMS-21BM: 1.68 (log10 µM)
Synonyms: KMS-21BM, KMS21BM
KMS-20: 1.66 (log10 µM)
Synonyms: KMS-20, KMS20
MOLT-13: 1.65 (log10 µM)
Synonyms: MOLT-13, MOLT13
KMS-34: 1.64 (log10 µM)
Synonyms: KMS-34, KMS34
JVM-2: 1.63 (log10 µM)
Synonyms: JVM-2, JVM2
SK-N-MC: 1.62 (log10 µM)
Synonyms: SK-N-MC, SKNMC
BT239: 1.58 (log10 µM)
Synonyms: BT239
PEER: 1.56 (log10 µM)
Synonyms: PEER
KMS-28BM: 1.52 (log10 µM)
Synonyms: KMS-28BM, KMS28BM
697: 1.52 (log10 µM)
Synonyms: 697
P12-ICHIKAWA: 1.49 (log10 µM)
Synonyms: P12-ICHIKAWA, P12ICHIKAWA
LP-1: 1.28 (log10 µM)
Synonyms: LP-1, LP1
MV-4-11: 1.28 (log10 µM)
Synonyms: MV-4-11, MV411
COR-L51: 1.25 (log10 µM)
Synonyms: COR-L51, CORL51
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
phloretin: AAC
AAC
Tissues
0.05
0.10
0.15
0.20
0.25
0.30
0.35
pancreas
pancreas
kidney
kidney
skin
skin
central_nervous_system
central_nervous_system
upper_aerodigestive_tract
upper_aerodigestive_tract
large_intestine
large_intestine
pleura
pleura
oesophagus
oesophagus
salivary_gland
salivary_gland
breast
breast
thyroid
thyroid
endometrium
endometrium
biliary_tract
biliary_tract
stomach
stomach
liver
liver
ovary
ovary
bone
bone
urinary_tract
urinary_tract
lung
lung
soft_tissue
soft_tissue
unknown
unknown
prostate
prostate
autonomic_ganglia
autonomic_ganglia
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
cervix
cervix
1.10
1.15
1.20
1.25
1.30
1.35
1.40
1.45
cervix
cervix
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
autonomic_ganglia
autonomic_ganglia
prostate
prostate
unknown
unknown
lung
lung
soft_tissue
soft_tissue
ovary
ovary
urinary_tract
urinary_tract
bone
bone
stomach
stomach
liver
liver
endometrium
endometrium
breast
breast
biliary_tract
biliary_tract
salivary_gland
salivary_gland
oesophagus
oesophagus
thyroid
thyroid
pleura
pleura
large_intestine
large_intestine
upper_aerodigestive_tract
upper_aerodigestive_tract
central_nervous_system
central_nervous_system
skin
skin
kidney
kidney
pancreas
pancreas
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to phloretin
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
PIK3R4
CTRPv2
pan-cancer
AAC
0.093
0.006
mRNA
LEMD3
CTRPv2
pan-cancer
AAC
0.095
0.006
mRNA
UBXN2A
CTRPv2
pan-cancer
AAC
0.094
0.006
mRNA
NPAS2
CTRPv2
pan-cancer
AAC
-0.097
0.006
mRNA
AAMP
CTRPv2
pan-cancer
AAC
-0.095
0.006
mRNA
MEIOB
CTRPv2
pan-cancer
AAC
0.096
0.006
mRNA
NSMCE4A
CTRPv2
pan-cancer
AAC
0.1
0.006
mRNA
GAMT
CTRPv2
pan-cancer
AAC
0.097
0.006
mRNA
SETMAR
CTRPv2
pan-cancer
AAC
0.1
0.006
mRNA
CHMP2B
CTRPv2
pan-cancer
AAC
-0.1
0.006
← Previous
1
2
…
165
166
167
…
199
200
Next →
Download CSV