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LE-135

LE-135

Synonyms

Sources	Names Used
CTRPv2	LE-135
PharmacoGx	LE-135

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C
Inchikey:	YZZAIQOVMHVWBS-UHFFFAOYSA-N
Pubchem:	10410894

Annotated Targets

FDA Approval Status

Not Approved

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Top molecular features associated with response to LE-135

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRKRA	CTRPv2	pan-cancer	AAC	0.072	0.05
mRNA	ADCY3	CTRPv2	pan-cancer	AAC	0.071	0.05
mRNA	POLD4	CTRPv2	pan-cancer	AAC	-0.073	0.05
mRNA	MAGEA8	CTRPv2	pan-cancer	AAC	0.07	0.05
mRNA	UBQLN2	CTRPv2	pan-cancer	AAC	0.072	0.05
mRNA	MPP6	CTRPv2	pan-cancer	AAC	0.073	0.05
mRNA	PFKFB1	CTRPv2	pan-cancer	AAC	0.072	0.05
mRNA	TLL1	CTRPv2	pan-cancer	AAC	0.07	0.05
mRNA	TTC4	CTRPv2	pan-cancer	AAC	0.072	0.05
mRNA	C1orf116	CTRPv2	pan-cancer	AAC	-0.083	0.05

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