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LE-135

LE-135

Synonyms

Sources	Names Used
CTRPv2	LE-135
PharmacoGx	LE-135

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C
Inchikey:	YZZAIQOVMHVWBS-UHFFFAOYSA-N
Pubchem:	10410894

Annotated Targets

FDA Approval Status

Not Approved

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Top molecular features associated with response to LE-135

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RECQL	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	ZNF202	CTRPv2	pan-cancer	AAC	0.14	0.0004
mRNA	PRPF38B	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	SMIM1	CTRPv2	pan-cancer	AAC	-0.13	0.0004
mRNA	SENP6	CTRPv2	pan-cancer	AAC	0.13	0.0004
mRNA	HNRNPA2B1	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	DCAF8L2	CTRPv2	pan-cancer	AAC	0.12	0.0005
mRNA	RAB37	CTRPv2	pan-cancer	AAC	-0.14	0.0005
mRNA	NBR1	CTRPv2	pan-cancer	AAC	-0.13	0.0005
mRNA	RAPH1	CTRPv2	pan-cancer	AAC	-0.14	0.0005

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