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LE-135

LE-135

Synonyms

Sources	Names Used
CTRPv2	LE-135
PharmacoGx	LE-135

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C
Inchikey:	YZZAIQOVMHVWBS-UHFFFAOYSA-N
Pubchem:	10410894

Annotated Targets

FDA Approval Status

Not Approved

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Top molecular features associated with response to LE-135

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RP11-407P15.2	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ADGRF3	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	ZNF511-PRAP1	CTRPv2	pan-cancer	AAC	-0.14	0.001
mRNA	RNF43	CTRPv2	pan-cancer	AAC	-0.15	0.001
mRNA	CEP192	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	SUV39H2	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	FAIM	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	POLQ	CTRPv2	pan-cancer	AAC	0.13	0.001
mRNA	CCR7	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	SMIM24	CTRPv2	pan-cancer	AAC	-0.12	0.001

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