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Merck60

Merck60

Synonyms

Sources	Names Used
CTRPv2	Merck60
PharmacoGx	Merck60

External IDs

Database	Identifier
Smiles:	CC(=O)Nc1ccc(cc1)C(=O)Nc2cc(ccc2N)c3cccs3

Annotated Targets

HDAC1, HDAC2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Merck60

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KIF3B	CTRPv2	pan-cancer	AAC	-0.13	0.0001
mRNA	CASP8AP2	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	HNRNPDL	CTRPv2	pan-cancer	AAC	0.13	0.0001
mRNA	DEFA5	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	SBK1	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	PRSS57	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	HES6	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	ATAD5	CTRPv2	pan-cancer	AAC	0.13	0.0001
mRNA	KDM1A	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	APOC4-APOC2	CTRPv2	pan-cancer	AAC	0.11	0.0001

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