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YK 4-279

YK 4-279

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	YK 4-279
PharmacoGx	YK 4-279

External IDs

Database	Identifier
Smiles:	COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl

Annotated Targets

EWSR1, FLI1, DHX9, ERG, ETV1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to YK 4-279

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF724	CTRPv2	pan-cancer	AAC	0.11	0.0009
mRNA	CPN1	CTRPv2	pan-cancer	AAC	-0.13	0.0009
mRNA	TUBE1	GDSC1000	pan-cancer	AAC	0.12	0.0009
mRNA	MCM5	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	ADPRM	GDSC1000	pan-cancer	AAC	0.13	0.0009
mRNA	CYB5RL	CTRPv2	pan-cancer	AAC	0.11	0.0009
mRNA	LRP10	CTRPv2	pan-cancer	AAC	-0.11	0.0009
mRNA	PTX3	GDSC1000	pan-cancer	AAC	0.13	0.0009
mRNA	LOXL2	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	NOL9	CTRPv2	pan-cancer	AAC	0.11	0.0009

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