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YK 4-279

Synonyms

SourcesNames Used
GDSC1000, CTRPv2YK 4-279
PharmacoGx YK 4-279

External IDs

DatabaseIdentifier
Smiles: COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl

Annotated Targets

EWSR1, FLI1, DHX9, ERG, ETV1

FDA Approval Status

Not Approved
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Top molecular features associated with response to YK 4-279


Feature TypeStandardized
Nominal ANOVA
mRNA THUMPD2 CTRPv2 pan-cancer AAC 0.11 0.001
mRNA LUC7L3 CTRPv2 pan-cancer AAC 0.11 0.001
mRNA ZNF687 CTRPv2 pan-cancer AAC 0.1 0.001
mRNA GATA3 CTRPv2 pan-cancer AAC -0.13 0.001
mRNA SHISA4 CTRPv2 pan-cancer AAC -0.13 0.001
mRNA FKTN GDSC1000 pan-cancer AAC 0.12 0.001
mRNA ZNF441 GDSC1000 pan-cancer AAC -0.12 0.001
mRNA ADGRL1 CTRPv2 pan-cancer AAC 0.11 0.001
mRNA HOXA9 CTRPv2 pan-cancer AAC 0.11 0.001
mRNA RP11-196G11.1 CTRPv2 pan-cancer AAC -0.12 0.001
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