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YK 4-279

Synonyms

SourcesNames Used
GDSC1000, CTRPv2YK 4-279
PharmacoGx YK 4-279

External IDs

DatabaseIdentifier
Smiles: COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl

Annotated Targets

EWSR1, FLI1, DHX9, ERG, ETV1

FDA Approval Status

Not Approved
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Top molecular features associated with response to YK 4-279


Feature TypeStandardized
Nominal ANOVA
mRNA FRAT2 CTRPv2 pan-cancer AAC 0.12 0.0008
mRNA RBMS2 CTRPv2 pan-cancer AAC -0.12 0.0008
mRNA HDAC11 CTRPv2 pan-cancer AAC -0.12 0.0008
mRNA LOX CTRPv2 pan-cancer AAC -0.11 0.0008
mRNA AUTS2 CTRPv2 pan-cancer AAC 0.11 0.0008
mRNA DBX2 CTRPv2 pan-cancer AAC 0.11 0.0008
mRNA MRPL50 GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA SCFD1 CTRPv2 pan-cancer AAC -0.11 0.0008
mRNA EPHA10 GDSC1000 pan-cancer AAC -0.13 0.0008
mRNA LYRM4 GDSC1000 pan-cancer AAC 0.13 0.0008
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