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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA CYCS CTRPv2 pan-cancer AAC 0.067 0.08
mRNA SLC41A3 CTRPv2 pan-cancer AAC -0.066 0.08
mRNA DDX43 CTRPv2 pan-cancer AAC -0.065 0.08
mRNA NT5DC2 CTRPv2 pan-cancer AAC 0.069 0.08
mRNA REEP4 CTRPv2 pan-cancer AAC -0.066 0.08
mRNA TKTL1 CTRPv2 pan-cancer AAC 0.063 0.08
mRNA C9orf69 CTRPv2 pan-cancer AAC -0.066 0.08
mRNA PCDHA8 CTRPv2 pan-cancer AAC 0.073 0.08
mRNA ZNF236 CTRPv2 pan-cancer AAC 0.066 0.08
mRNA PIP5K1B CTRPv2 pan-cancer AAC -0.071 0.08
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