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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS50 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA CACNG3 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA LYG1 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA PRRC2C CTRPv2 pan-cancer AAC 0.13 0.001
mRNA HEATR1 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA GTF3C2 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA NDUFC2-KCTD14 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA LCN8 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA SNX3 CTRPv2 pan-cancer AAC -0.12 0.002
mRNA ROPN1 CTRPv2 pan-cancer AAC 0.12 0.002
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