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necrostatin-1

Synonyms

SourcesNames Used
CTRPv2necrostatin-1
PharmacoGx necrostatin-1

External IDs

DatabaseIdentifier
Smiles: CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Inchikey: TXUWMXQFNYDOEZ-UHFFFAOYSA-N
Pubchem: 2828334

Annotated Targets

RIPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to necrostatin-1


Feature TypeStandardized
Nominal ANOVA
mRNA PSMC4 CTRPv2 pan-cancer AAC 0.12 0.0009
mRNA CADM1 CTRPv2 pan-cancer AAC 0.13 0.0009
mRNA SPDYE2 CTRPv2 pan-cancer AAC 0.13 0.0009
mRNA SLCO5A1 CTRPv2 pan-cancer AAC 0.13 0.0009
mRNA MED1 CTRPv2 pan-cancer AAC 0.12 0.0009
mRNA FNBP4 CTRPv2 pan-cancer AAC 0.13 0.0009
mRNA REG1A CTRPv2 pan-cancer AAC 0.12 0.001
mRNA GH1 CTRPv2 pan-cancer AAC 0.13 0.001
mRNA MYLK2 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA ARHGEF26 CTRPv2 pan-cancer AAC 0.12 0.001
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