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itraconazole

Synonyms

SourcesNames Used
CTRPv2itraconazole
PharmacoGx itraconazole

External IDs

DatabaseIdentifier
Smiles: CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
Inchikey: VHVPQPYKVGDNFY-TUJWMRSMSA-N
Pubchem: 14179013

Annotated Targets

CYP51A1

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to itraconazole


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF337 CTRPv2 pan-cancer AAC 0.15 4e-05
mRNA RAB44 CTRPv2 pan-cancer AAC 0.16 4e-05
mRNA ZDHHC14 CTRPv2 pan-cancer AAC 0.15 5e-05
mRNA SPN CTRPv2 pan-cancer AAC 0.21 5e-05
mRNA NRROS CTRPv2 pan-cancer AAC 0.2 5e-05
mRNA SLC29A1 CTRPv2 pan-cancer AAC 0.16 5e-05
mRNA GAPDH CTRPv2 pan-cancer AAC -0.16 6e-05
mRNA DLX4 CTRPv2 pan-cancer AAC 0.15 6e-05
mRNA GOLGA8O CTRPv2 pan-cancer AAC 0.16 7e-05
mRNA SNX20 CTRPv2 pan-cancer AAC 0.19 7e-05
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