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GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA TBX1 GDSC1000 pan-cancer AAC 0.12 0.0001
mRNA PANK1 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA ACTN4 GDSC1000 pan-cancer AAC -0.14 0.0001
mRNA VPREB1 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA DOK3 GDSC1000 pan-cancer AAC 0.17 0.0001
mRNA ILK GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA TMEM158 GDSC1000 pan-cancer AAC -0.14 0.0001
mRNA NNMT GDSC1000 pan-cancer AAC -0.15 0.0001
mRNA SBK1 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA UGGT2 GDSC1000 pan-cancer AAC -0.12 0.0002
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