1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA SQSTM1 GDSC1000 pan-cancer AAC -0.15 4e-05
mRNA PRKX GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA HIST1H1D GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA LIPI GDSC1000 pan-cancer AAC 0.16 4e-05
mRNA CALU GDSC1000 pan-cancer AAC -0.17 4e-05
mRNA SH3BP5 GDSC1000 pan-cancer AAC -0.13 4e-05
mRNA GPR18 GDSC1000 pan-cancer AAC 0.17 4e-05
mRNA BEND3 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA LAMA1 GDSC1000 pan-cancer AAC -0.14 4e-05
mRNA RABL6 GDSC1000 pan-cancer AAC 0.13 4e-05
Download CSV