1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA SYNGR3 GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA MAGEB2 GDSC1000 pan-cancer AAC -0.11 0.0003
mRNA CWF19L2 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA TNRC6B GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA PPP1R1A GDSC1000 pan-cancer AAC 0.14 0.0003
mRNA ENPP2 GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA GAB1 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA C19orf18 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA NLRC3 GDSC1000 pan-cancer AAC 0.17 0.0003
mRNA ZBTB5 GDSC1000 pan-cancer AAC 0.12 0.0003
Download CSV