1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM167B GDSC1000 pan-cancer AAC -0.076 0.02
mRNA COL6A1 GDSC1000 pan-cancer AAC -0.092 0.02
mRNA TXN GDSC1000 pan-cancer AAC -0.08 0.02
mRNA PARVG GDSC1000 pan-cancer AAC 0.092 0.02
mRNA CCDC53 GDSC1000 pan-cancer AAC -0.074 0.02
mRNA FRAT2 GDSC1000 pan-cancer AAC 0.085 0.02
mRNA CDC42BPG GDSC1000 pan-cancer AAC 0.076 0.02
mRNA CRABP1 GDSC1000 pan-cancer AAC 0.082 0.02
mRNA HMGN3 GDSC1000 pan-cancer AAC 0.076 0.02
mRNA HES3 GDSC1000 pan-cancer AAC -0.073 0.02
Download CSV