1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA MED12 GDSC1000 pan-cancer AAC 0.1 0.002
mRNA SBDS GDSC1000 pan-cancer AAC -0.11 0.002
mRNA WHSC1L1 GDSC1000 pan-cancer AAC 0.1 0.002
mRNA ZNF675 GDSC1000 pan-cancer AAC 0.11 0.002
mRNA SMO GDSC1000 pan-cancer AAC 0.11 0.002
mRNA ZNF90 GDSC1000 pan-cancer AAC 0.1 0.002
mRNA TGFB1I1 GDSC1000 pan-cancer AAC -0.12 0.002
mRNA DPH3 GDSC1000 pan-cancer AAC -0.1 0.002
mRNA JKAMP GDSC1000 pan-cancer AAC -0.11 0.002
mRNA E2F3 GDSC1000 pan-cancer AAC 0.11 0.002
Download CSV