1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA CD72 GDSC1000 pan-cancer AAC 0.17 5e-06
mRNA SLC25A43 GDSC1000 pan-cancer AAC -0.16 5e-06
mRNA CCAR1 GDSC1000 pan-cancer AAC 0.16 5e-06
mRNA SECISBP2 GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA USF1 GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA BRD3 GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA DLG2 GDSC1000 pan-cancer AAC 0.17 5e-06
mRNA ZNF107 GDSC1000 pan-cancer AAC 0.18 5e-06
mRNA PMP22 GDSC1000 pan-cancer AAC -0.17 6e-06
mRNA HPCAL1 GDSC1000 pan-cancer AAC -0.15 6e-06
Download CSV