1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA VAMP3 GDSC1000 pan-cancer AAC -0.13 0.0007
mRNA PANK2 GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA RASSF8 GDSC1000 pan-cancer AAC -0.12 0.0007
mRNA ARID5B GDSC1000 pan-cancer AAC 0.11 0.0007
mRNA STK38 GDSC1000 pan-cancer AAC 0.11 0.0008
mRNA SDF4 GDSC1000 pan-cancer AAC -0.11 0.0008
mRNA TMBIM1 GDSC1000 pan-cancer AAC -0.13 0.0008
mRNA SYNCRIP GDSC1000 pan-cancer AAC 0.11 0.0008
mRNA FAM110A GDSC1000 pan-cancer AAC 0.12 0.0008
mRNA FGD3 GDSC1000 pan-cancer AAC 0.13 0.0008
Download CSV