1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA MED22 GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA TAF4 GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA GADD45A GDSC1000 pan-cancer AAC -0.11 0.0004
mRNA CBFA2T3 GDSC1000 pan-cancer AAC 0.14 0.0004
mRNA UBAP2 GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA PRKD1 GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA LRRFIP2 GDSC1000 pan-cancer AAC -0.11 0.0004
mRNA TNFRSF12A GDSC1000 pan-cancer AAC -0.16 0.0004
mRNA NEIL1 GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA STAMBPL1 GDSC1000 pan-cancer AAC -0.12 0.0004
Download CSV