1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA TEX9 GDSC1000 pan-cancer AAC 0.11 0.0004
mRNA TEAD2 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA SMARCA4 GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA WTAP GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA RCN3 GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA KIAA1644 GDSC1000 pan-cancer AAC -0.12 0.0004
mRNA DDAH1 GDSC1000 pan-cancer AAC -0.13 0.0004
mRNA DCP2 GDSC1000 pan-cancer AAC 0.14 0.0004
mRNA ICAM1 GDSC1000 pan-cancer AAC -0.12 0.0004
mRNA IKBIP GDSC1000 pan-cancer AAC -0.13 0.0004
Download CSV