1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA CPQ GDSC1000 pan-cancer AAC -0.13 0.0003
mRNA FANCF GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA CD276 GDSC1000 pan-cancer AAC -0.15 0.0003
mRNA RAB32 GDSC1000 pan-cancer AAC -0.13 0.0003
mRNA CIRBP GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA C3orf62 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA BUD13 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA CREB1 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA TMEM9B GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA SPRYD7 GDSC1000 pan-cancer AAC -0.11 0.0003
Download CSV