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GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA NCKAP1 GDSC1000 pan-cancer AAC -0.29 1e-06
mRNA PIK3CG GDSC1000 pan-cancer AAC 0.22 1e-06
mRNA RBBP6 GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA RMI1 GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA ZNF84 GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA RBM12B GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA CD59 GDSC1000 pan-cancer AAC -0.18 2e-06
mRNA HNRNPA1L2 GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA CDK13 GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA ZNF292 GDSC1000 pan-cancer AAC 0.16 3e-06
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