1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA SCN8A GDSC1000 pan-cancer AAC -0.075 0.02
mRNA LINGO1 GDSC1000 pan-cancer AAC 0.081 0.02
mRNA TXLNA GDSC1000 pan-cancer AAC -0.077 0.02
mRNA PQLC1 GDSC1000 pan-cancer AAC 0.075 0.02
mRNA PIM1 GDSC1000 pan-cancer AAC -0.077 0.02
mRNA PGLYRP4 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA CEP192 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA IMMP2L GDSC1000 pan-cancer AAC -0.08 0.02
mRNA UBL3 GDSC1000 pan-cancer AAC -0.081 0.02
mRNA YRDC GDSC1000 pan-cancer AAC -0.077 0.02
Download CSV