1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA AOC3 GDSC1000 pan-cancer AAC -0.074 0.02
mRNA CDK20 GDSC1000 pan-cancer AAC 0.077 0.02
mRNA FAM214A GDSC1000 pan-cancer AAC 0.08 0.02
mRNA APMAP GDSC1000 pan-cancer AAC -0.081 0.02
mRNA DYNC1LI2 GDSC1000 pan-cancer AAC -0.094 0.02
mRNA UEVLD GDSC1000 pan-cancer AAC -0.087 0.02
mRNA SGCB GDSC1000 pan-cancer AAC -0.09 0.02
mRNA FBXL20 GDSC1000 pan-cancer AAC 0.074 0.02
mRNA HMGN5 GDSC1000 pan-cancer AAC 0.084 0.02
mRNA SLAMF9 GDSC1000 pan-cancer AAC -0.078 0.02
Download CSV