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GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF227 GDSC1000 pan-cancer AAC 0.083 0.01
mRNA FZD3 GDSC1000 pan-cancer AAC 0.081 0.01
mRNA EIF3E GDSC1000 pan-cancer AAC 0.083 0.01
mRNA THOC5 GDSC1000 pan-cancer AAC -0.081 0.01
mRNA BTG3 GDSC1000 pan-cancer AAC -0.078 0.01
mRNA ZAP70 GDSC1000 pan-cancer AAC 0.084 0.01
mRNA TEAD1 GDSC1000 pan-cancer AAC -0.086 0.01
mRNA YTHDF3 GDSC1000 pan-cancer AAC 0.076 0.01
mRNA SMIM8 GDSC1000 pan-cancer AAC 0.085 0.01
mRNA ASB5 GDSC1000 pan-cancer AAC -0.077 0.01
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