1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA E2F5 GDSC1000 pan-cancer AAC 0.084 0.01
mRNA CHRDL1 GDSC1000 pan-cancer AAC -0.082 0.01
mRNA SPINT1 GDSC1000 pan-cancer AAC 0.11 0.01
mRNA ARHGAP31 GDSC1000 pan-cancer AAC -0.09 0.01
mRNA SF1 GDSC1000 pan-cancer AAC 0.09 0.01
mRNA NDRG2 GDSC1000 pan-cancer AAC 0.083 0.01
mRNA PRODH GDSC1000 pan-cancer AAC 0.082 0.01
mRNA MAP4 GDSC1000 pan-cancer AAC -0.089 0.01
mRNA MPLKIP GDSC1000 pan-cancer AAC 0.082 0.01
mRNA COG2 GDSC1000 pan-cancer AAC 0.087 0.01
Download CSV