1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA SLC14A2 GDSC1000 pan-cancer AAC 0.082 0.01
mRNA RABL2A GDSC1000 pan-cancer AAC 0.081 0.01
mRNA ARMCX2 GDSC1000 pan-cancer AAC -0.091 0.01
mRNA ARGLU1 GDSC1000 pan-cancer AAC 0.088 0.01
mRNA TMEM64 GDSC1000 pan-cancer AAC -0.082 0.01
mRNA TRAFD1 GDSC1000 pan-cancer AAC 0.085 0.01
mRNA RTN4RL1 GDSC1000 pan-cancer AAC 0.084 0.01
mRNA GEN1 GDSC1000 pan-cancer AAC 0.091 0.01
mRNA CHCHD5 GDSC1000 pan-cancer AAC -0.081 0.01
mRNA ERCC6L2 GDSC1000 pan-cancer AAC 0.081 0.01
Download CSV