1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA EHD2 GDSC1000 pan-cancer AAC -0.092 0.009
mRNA AC013461.1 GDSC1000 pan-cancer AAC -0.086 0.009
mRNA COG5 GDSC1000 pan-cancer AAC -0.081 0.009
mRNA TPR GDSC1000 pan-cancer AAC 0.083 0.009
mRNA ZNF629 GDSC1000 pan-cancer AAC 0.092 0.009
mRNA KBTBD12 GDSC1000 pan-cancer AAC -0.08 0.009
mRNA USP37 GDSC1000 pan-cancer AAC 0.086 0.009
mRNA CCDC14 GDSC1000 pan-cancer AAC 0.082 0.009
mRNA AKAP7 GDSC1000 pan-cancer AAC 0.091 0.009
mRNA PQLC3 GDSC1000 pan-cancer AAC -0.086 0.009
Download CSV