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GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA THUMPD1 GDSC1000 pan-cancer AAC 0.087 0.008
mRNA WNT5B GDSC1000 pan-cancer AAC -0.087 0.008
mRNA CRYZ GDSC1000 pan-cancer AAC -0.089 0.008
mRNA ZCCHC24 GDSC1000 pan-cancer AAC -0.097 0.008
mRNA ELOVL1 GDSC1000 pan-cancer AAC -0.092 0.008
mRNA NDUFAF6 GDSC1000 pan-cancer AAC 0.088 0.008
mRNA RPL9 GDSC1000 pan-cancer AAC 0.091 0.008
mRNA FAM96B GDSC1000 pan-cancer AAC -0.084 0.009
mRNA ZHX2 GDSC1000 pan-cancer AAC 0.089 0.009
mRNA EIF3I GDSC1000 pan-cancer AAC -0.083 0.009
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