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GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA KIAA1958 GDSC1000 pan-cancer AAC 0.091 0.008
mRNA MAFG GDSC1000 pan-cancer AAC -0.085 0.008
mRNA NR2C1 GDSC1000 pan-cancer AAC 0.086 0.008
mRNA IL10RB GDSC1000 pan-cancer AAC -0.092 0.008
mRNA FAT2 GDSC1000 pan-cancer AAC 0.11 0.008
mRNA MRPL33 GDSC1000 pan-cancer AAC -0.087 0.008
mRNA ARPC5 GDSC1000 pan-cancer AAC -0.084 0.008
mRNA BRF2 GDSC1000 pan-cancer AAC 0.083 0.008
mRNA HIGD1C GDSC1000 pan-cancer AAC 0.084 0.008
mRNA HNRNPF GDSC1000 pan-cancer AAC 0.09 0.008
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