1. Home/
  2. Compounds/
  3. GSK2126458

GSK2126458

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK2126458
PharmacoGx GSK2126458

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
Inchikey: CGBJSGAELGCMKE-UHFFFAOYSA-N
Pubchem: 25167777

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK2126458


Feature TypeStandardized
Nominal ANOVA
mRNA RBM5 GDSC1000 pan-cancer AAC 0.098 0.007
mRNA GNB5 GDSC1000 pan-cancer AAC -0.089 0.007
mRNA TENM3 GDSC1000 pan-cancer AAC -0.095 0.007
mRNA PLPP4 GDSC1000 pan-cancer AAC -0.092 0.007
mRNA MFSD12 GDSC1000 pan-cancer AAC -0.11 0.008
mRNA GATAD2B GDSC1000 pan-cancer AAC 0.093 0.008
mRNA COPZ2 GDSC1000 pan-cancer AAC -0.097 0.008
mRNA CLDND1 GDSC1000 pan-cancer AAC -0.087 0.008
mRNA UPF2 GDSC1000 pan-cancer AAC 0.095 0.008
mRNA IVNS1ABP GDSC1000 pan-cancer AAC 0.085 0.008
Download CSV