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Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

FDA Approval Status

Approved
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Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA CCDC159 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA PDE9A CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA RECK CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA GOLT1A CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA HTR3B CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA PIRT CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA IFRD1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA TEX10 CTRPv2 pan-cancer AAC -0.15 0.0002
mRNA BCL2L11 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA TCTE1 CTRPv2 pan-cancer AAC 0.15 0.0002
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