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Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

FDA Approval Status

Approved
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Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA TRIAP1 CTRPv2 pan-cancer AAC -0.073 0.06
mRNA ZDHHC19 CTRPv2 pan-cancer AAC -0.071 0.06
mRNA FGF14 CTRPv2 pan-cancer AAC 0.071 0.06
mRNA MSMO1 CTRPv2 pan-cancer AAC 0.072 0.06
mRNA CAV1 CTRPv2 pan-cancer AAC -0.078 0.06
mRNA ACOT4 CTRPv2 pan-cancer AAC -0.077 0.06
mRNA ZBTB26 CTRPv2 pan-cancer AAC -0.073 0.06
mRNA NKD2 CTRPv2 pan-cancer AAC 0.073 0.06
mRNA PCDH15 CTRPv2 pan-cancer AAC -0.07 0.06
mRNA ARHGAP10 CTRPv2 pan-cancer AAC -0.072 0.06
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