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Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

FDA Approval Status

Approved
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Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA HRASLS5 CTRPv2 pan-cancer AAC 0.07 0.06
mRNA KCTD9 CTRPv2 pan-cancer AAC -0.073 0.06
mRNA CFL1 CTRPv2 pan-cancer AAC -0.072 0.06
mRNA GOLM1 CTRPv2 pan-cancer AAC -0.078 0.06
mRNA MOV10 CTRPv2 pan-cancer AAC -0.073 0.06
mRNA OAZ1 CTRPv2 pan-cancer AAC 0.078 0.06
mRNA CHD1 CTRPv2 pan-cancer AAC -0.073 0.06
mRNA BNC2 CTRPv2 pan-cancer AAC -0.076 0.06
mRNA ZWINT CTRPv2 pan-cancer AAC -0.072 0.06
mRNA SH3RF1 CTRPv2 pan-cancer AAC 0.077 0.06
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