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Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

FDA Approval Status

Approved
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Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA SERHL2 CTRPv2 pan-cancer AAC 0.074 0.06
mRNA BANF2 CTRPv2 pan-cancer AAC 0.072 0.06
mRNA TRIM39-RPP21 CTRPv2 pan-cancer AAC -0.074 0.06
mRNA DHX34 CTRPv2 pan-cancer AAC -0.075 0.06
mRNA HAGHL CTRPv2 pan-cancer AAC 0.077 0.06
mRNA ARIH2 CTRPv2 pan-cancer AAC -0.077 0.06
mRNA SOX15 CTRPv2 pan-cancer AAC -0.091 0.06
mRNA CLCC1 CTRPv2 pan-cancer AAC -0.076 0.06
mRNA RPN2 CTRPv2 pan-cancer AAC 0.074 0.06
mRNA PPP4C CTRPv2 pan-cancer AAC -0.073 0.06
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