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Sildenafil

Synonyms

SourcesNames Used
CTRPv2sildenafil
PharmacoGx Sildenafil

External IDs

DatabaseIdentifier
Smiles: CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
Inchikey: BNRNXUUZRGQAQC-UHFFFAOYSA-N
Pubchem: 5212

Annotated Targets

PDE5A, PDE6G, PDE6H, SLCO1B1, SLCO1B3

FDA Approval Status

Approved
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Top molecular features associated with response to Sildenafil


Feature TypeStandardized
Nominal ANOVA
mRNA PRR30 CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA CALML5 CTRPv2 pan-cancer AAC 0.16 7e-05
mRNA REL CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA KCNT1 CTRPv2 pan-cancer AAC 0.15 9e-05
mRNA TMEM14B CTRPv2 pan-cancer AAC -0.15 0.0001
mRNA SYNPO2 CTRPv2 pan-cancer AAC 0.16 0.0001
mRNA EEF1E1 CTRPv2 pan-cancer AAC -0.15 0.0001
mRNA CAPS CTRPv2 pan-cancer AAC 0.14 0.0001
mRNA UQCRFS1 CTRPv2 pan-cancer AAC 0.14 0.0001
mRNA FBLN5 CTRPv2 pan-cancer AAC 0.15 0.0002
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