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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA SLFN11 GDSC1000 pan-cancer AAC 0.5 8e-48
mRNA SLFN11 CTRPv2 pan-cancer AAC 0.46 1e-36
mRNA NCKAP1L CTRPv2 pan-cancer AAC 0.31 1e-09
mRNA SEPT6 GDSC1000 pan-cancer AAC 0.31 4e-10
mRNA ELAVL1 CTRPv2 pan-cancer AAC 0.31 3e-15
mRNA HMGB2 CTRPv2 pan-cancer AAC 0.3 7e-12
mRNA ARHGAP19 CTRPv2 pan-cancer AAC 0.29 4e-11
mRNA ARHGAP19-SLIT1 CTRPv2 pan-cancer AAC 0.29 8e-12
mRNA KLHL23 CTRPv2 pan-cancer AAC 0.29 4e-13
mRNA KHDRBS1 CTRPv2 pan-cancer AAC 0.29 3e-14
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