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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA AGO3 CTRPv2 pan-cancer AAC 0.23 7e-10
mRNA IPO9 CTRPv2 pan-cancer AAC 0.23 7e-10
mRNA FBXO5 CTRPv2 pan-cancer AAC 0.24 7e-10
mRNA ZNF22 CTRPv2 pan-cancer AAC 0.25 8e-10
mRNA MARCKSL1 CTRPv2 pan-cancer AAC 0.22 1e-09
mRNA NCKAP1L CTRPv2 pan-cancer AAC 0.31 1e-09
mRNA SHPRH CTRPv2 pan-cancer AAC 0.25 1e-09
mRNA NASP CTRPv2 pan-cancer AAC 0.23 1e-09
mRNA ATP6V0A1 GDSC1000 pan-cancer AAC -0.2 1e-09
mRNA ZNF253 CTRPv2 pan-cancer AAC 0.23 2e-09
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