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SN-38

SN-38

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	SN-38
PharmacoGx	SN-38

External IDs

Database	Identifier
Smiles:	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey:	FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem:	104842

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SN-38

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KLHL23	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	SMARCA4	CTRPv2	pan-cancer	AAC	0.15	0.0002
mRNA	OSBPL7	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	OSGIN1	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	PSMC3IP	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	ENHO	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	DNAJC12	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	ZNF10	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	KCNN3	GDSC1000	pan-cancer	AAC	-0.13	0.0003
mRNA	MED30	CTRPv2	pan-cancer	AAC	0.14	0.0003

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