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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA C7orf26 GDSC1000 pan-cancer AAC 0.2 5e-09
mRNA CTCF CTRPv2 pan-cancer AAC 0.24 5e-09
mRNA ALMS1 CTRPv2 pan-cancer AAC 0.22 5e-09
mRNA ZNF397 CTRPv2 pan-cancer AAC 0.22 6e-09
mRNA ILF3 CTRPv2 pan-cancer AAC 0.23 6e-09
mRNA TCTA GDSC1000 pan-cancer AAC -0.2 7e-09
mRNA ATP6V1G2-DDX39B CTRPv2 pan-cancer AAC 0.22 7e-09
mRNA ZFP1 CTRPv2 pan-cancer AAC 0.22 7e-09
mRNA HNRNPA1L2 CTRPv2 pan-cancer AAC 0.25 8e-09
mRNA SFPQ CTRPv2 pan-cancer AAC 0.23 8e-09
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