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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA CLSPN CTRPv2 pan-cancer AAC 0.19 4e-07
mRNA FXR2 GDSC1000 pan-cancer AAC 0.17 4e-07
mRNA GIMAP7 GDSC1000 pan-cancer AAC 0.17 4e-07
mRNA MDM4 CTRPv2 pan-cancer AAC 0.22 4e-07
mRNA DDX39B CTRPv2 pan-cancer AAC 0.19 4e-07
mRNA EDEM2 CTRPv2 pan-cancer AAC -0.19 4e-07
mRNA GMEB1 CTRPv2 pan-cancer AAC 0.21 4e-07
mRNA KRI1 CTRPv2 pan-cancer AAC 0.22 4e-07
mRNA PHF6 CTRPv2 pan-cancer AAC 0.19 4e-07
mRNA SRSF7 CTRPv2 pan-cancer AAC 0.2 4e-07
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