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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA NBR1 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA ZIC3 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA MXRA8 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA TRAK1 GDSC1000 pan-cancer AAC -0.12 0.0004
mRNA SMC3 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA DNAJB2 CTRPv2 pan-cancer AAC -0.14 0.0004
mRNA ICOS GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA ATP6V1G2 CTRPv2 pan-cancer AAC 0.14 0.0004
mRNA MAD2L1 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA MSRB1 GDSC1000 pan-cancer AAC -0.12 0.0004
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