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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA EP400 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA RAG2 GDSC1000 pan-cancer AAC 0.13 0.0003
mRNA PHGDH CTRPv2 pan-cancer AAC 0.13 0.0003
mRNA ADNP CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA PLA2G4F GDSC1000 pan-cancer AAC -0.12 0.0003
mRNA SF3A3 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA SARDH CTRPv2 pan-cancer AAC 0.13 0.0003
mRNA POLE CTRPv2 pan-cancer AAC 0.13 0.0003
mRNA ZNF532 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA SNCB CTRPv2 pan-cancer AAC 0.13 0.0003
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